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Orly Weissberg

Neuroimmunology and Bioactive Compounds

The research focuses on neuroimmunology, investigating how immune mechanisms shape brain function in health and disease. It centers on the role of microglia and neuroinflammation in the development and progression of neurodevelopmental, neurodegenerative, and psychiatric disorders. The work examines key molecular pathways, including NF-κB and NLRP3, to identify mechanisms driving pathological changes in the brain. In addition, it explores bioactive compounds derived from natural sources such as fungi and algae as modulators of immune responses and as a foundation for developing innovative therapeutic strategies to support brain health.

Neuroimmunology and Bioactive Compounds
Research Interests

Neuroimmunology – Investigating interactions between the immune system and the nervous system in the context of neurodevelopmental, neurodegenerative, and psychiatric disorders.

Microglia and Neuroinflammation – Examining the role of microglial cells in inflammatory processes in the brain and their impact on neural function and behavior.

Molecular Inflammatory Pathways – Studying key inflammatory signaling pathways, including NF-κB and NLRP3, as well as the role of cytokines in these processes.

Bioactive Compounds from Natural Sources – Exploring the potential of fungi and algae as sources of bioactive molecules that modulate immune responses.